Cell migration (IMAGE) University of Helsinki Caption The rapidly growing actin filament plus-ends (+) elongating against the plasma membrane push the leading edge of cell forward to drive cell migration. Filament disassembly is believed to occur at their minus-ends (-) facing away from the plasma membrane. Credit Lappalainen research group, University of Helsinki Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.