Novel NAD+-degrading Toxin Triggers Cell Death of Tuberculosis-Causing Bacteria (IMAGE)

European Molecular Biology Laboratory

Novel NAD+-degrading Toxin Triggers Cell Death of Tuberculosis-Causing Bacteria

Caption

The illustration shows sections of Mycobacterium tuberculosis bacteria. The Pac-Man symbolizes the toxin, which in the absence of its antitoxin counterpart, ‘eats up’ the NAD+, causing the cell to die. In the bacterium in the back, the Pac-Man’s mouth is blocked by the antitoxin, preventing the degradation of NAD+ and allowing the cell to grow normally.

Credit

Beata Edyta Mierzwa

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