IRF2 Deficiency (IMAGE)

_Tokyo Medical and Dental University

IRF2 Deficiency

Caption

A. Flow cytometric analysis revealed that the number of ISCs was reduced in Irf2-/- mice compared with control mice. Lgr5-GFP: reporter fluorescence of ISCs. B. Sections of the jejunum from control (left) and Irf2-/- (right) mice, 6 days after the induction of epithelial injury by 5-fluorouracil administration, were stained with Ki67. The number of Ki67-stained regenerated crypts were substantially reduced in Irf2-/- mice compared with control mice.

Credit

Department of Biodefense Research,TMDU

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