Integrating machine learning with total network controllability analysis to identify therapeutic targets for cancer treatment (IMAGE)

The Hong Kong Polytechnic University

Integrating machine learning with total network controllability analysis to identify therapeutic targets for cancer treatment

Caption

Gene regulatory network construction and control hubs of complex networks (A) Construction of a gene regulatory network, GRN. Ten control-related gene/protein interaction types were extracted from five high-quality pathway databases. A breadth-first search was then performed, starting from 45 known BLCA driver genes and the 50 most highly mutated genes of

Credit

© 2025 Research and Innovation Office, The Hong Kong Polytechnic University. All Rights Reserved.

Usage Restrictions

nil

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.