Biosynthetic route to collagen fibers. Size and complexity are increased by posttranslational modifications and self-assembly. (IMAGE)

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Biosynthetic route to collagen fibers. Size and complexity are increased by posttranslational modifications and self-assembly.

Caption

Biosynthetic route to collagen fibers. Size and complexity are increased by posttranslational modifications and self-assembly. Oxidation of lysine side chains leads to the spontaneous formation of hydroxylysyl pyridinoline and lysyl pyridinoline cross-links.

Credit

Sheng Xiong, et al.

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License

CC BY-NC-ND

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