Inhibition of Muscarinic Signaling Alleviates Dopamine Release Reduction Caused by Nicotine Withdrawal (IMAGE)

National Research Council of Science & Technology

Inhibition of Muscarinic Signaling Alleviates Dopamine Release Reduction Caused by Nicotine Withdrawal

Caption

Nicotine withdrawal decreases dopamine release in the striatum. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine prevents this decrease in dopamine release.

Credit

Korea Institute of Science and Technology

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