Stress (IMAGE)
Caption
Stress granules are transient structures that assemble in response to cellular stress, temporarily halting nonessential processes to aid cell recovery. Under normal conditions, they protect the cell and dissipate once the stress is resolved. However, in Alzheimer’s disease, stress granules persist abnormally, becoming chronic and pathological. They trap essential molecules and disrupt their transport into and out of the cell nucleus, shifting from a protective role to a harmful one that contributes to disease progression.
Credit
Graphic by Jason Drees
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