Image link: https://ars.els-cdn.com/content/image/1-s2.0-S2352304224000898-gr1.jpg (IMAGE) Compuscript Ltd Caption Image caption: At the endpoint of the experiment, C26 tumor-bearing mice were executed, and tissues of interest were dissected for further analysis. (A) Representative images of GA and weight analysis and (B) CSA of myofibers in GA tissues and quantitative statistics. (C) Representative images of eWAT and weight analysis and (D) CSA of adipocytes in eWAT tissues and quantitative statistics. (E) Glycerol and (F) triglyceride levels in mice serum. (G) TNF-α levels and (H) IL-6 levels in mice serum. The data represent mean ± standard error of the mean; n = 8; ∗∗∗P < 0.001, ∗∗P < 0.01, ∗P < 0.05. CSA, cross-sectional area; eWAT, epididymal white fat; GA, gastrocnemius muscle; IL-6, interleukin 6; TNF-α, tumor necrosis factor α. Image link: https://ars.els-cdn.com/content/image/1-s2.0-S2352304224000898-gr4.jpg Credit The authors Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. License CC BY-NC-ND Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.