LPAR1 antagonist effectively alleviates Rgs22 deficiency-induced ventricular enlargement. (IMAGE)
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The representative MRI images of coronal sections, transverse sections and sagittal sections of Rgs22−/− rats before (left) or after (right) AM095 or LPAR2 antagonist treatment. Compared to the control group (LPAR2 antagonist treatment), the AM095-treated rats exhibited significant reduction in ventricular dilation. Photo credit: Xue Pang and Lin Gu.
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Photo credit: Xue Pang and Lin Gu.
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