Live-cell images of cells expressing CAAX-GCaMP6s in cells neighboring an irradiated cell (IMAGE)

Kyushu University

Live-cell images of cells expressing CAAX-GCaMP6s in cells neighboring an irradiated cell

Caption

In this image, the cell marked with an asterisk was damaged using a focused laser, triggering apoptosis. After an initial increase in general calcium levels around the dying cell (calcium wave), a sustained increase in calcium levels was observed at the interface between the apoptotic cell and the surrounding cells (marked B and D). This new mechanism is essential for expelling the apoptotic cell and preserving the integrity of the epithelium.

Credit

Junichi Ikenouchi, originally published in https://doi.org/10.1016/j.cub.2024.08.057

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Credit must be given to the creator.

License

CC BY

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