Xin Zhou, PhD (IMAGE) University of North Carolina Health Care Caption “Our findings demonstrate that CAR-NKT cells not only effectively eliminate CD1d-expressing M2-like macrophages within the tumor microenvironment but also stimulate endogenous immune cells,” said Xin Zhou, PhD, the paper’s first author and a UNC Lineberger postdoc. “This dual function—overcoming suppressive immune cells and promoting sustained immune activity—represents a crucial advancement in improving CAR-based therapies for solid tumors and achieving long-term tumor control.” Credit UNC Lineberger Comprehensive Cancer Center Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.