explained Preethy S. Sridharan, PhD (IMAGE)
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“We started with the hypothesis that TBI might pathologically impair the balance of mitochondrial fission and fusion,” explained Preethy S. Sridharan, PhD, lead author of the study. “The normal homeostatic balance of mitochondrial fission and fusion is how mitochondria consistently produce enough energy for the cell while also sequestering and disposing damaged parts. Given the very high energy demands of the brain, this is particularly important for brain health across our lifespan.”
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