MUSCLE paves the way for genome-scale single-molecule biophysics by enabling the comprehensive profiling of sequence dependence at the single-molecule level. (IMAGE)

Uppsala University

MUSCLE paves the way for genome-scale single-molecule biophysics by enabling the comprehensive profiling of sequence dependence at the single-molecule level.

Caption

In the cell, genome-interacting machinery encounters a very large number of different nucleic acid sequences. These sequences give rise to distinct energetic landscapes that modulate the intricate dynamics of genome transactions. MUSCLE paves the way for genome-scale single-molecule biophysics by enabling the comprehensive profiling of sequence dependence at the single-molecule level.

Credit

Deindl Lab

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