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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)

Graphical abstract

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Modified peptide derived from the natural CART peptide. After repeated administration to mice suffering from obesity and prediabetes, the mice began to eat less, lost weight, and their metabolism improved. Their brains showed reduced Tau protein pathology, and new nerve cells also began to form in their brains.

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Charvát et al. Eur. J. Pharmacol. 980 (2024) 176864

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