Distinct transcriptional profiles in chronic hepatitis B (CHB) biopsies. (IMAGE)

First Hospital of Jilin University

Distinct transcriptional profiles in chronic hepatitis B (CHB) biopsies.

Caption

Eigengene expression of each module (n=8) produced from a weighted gene correlation network analysis. Eigengene expression is annotated by the estimated HBV surface antigen (HBsAg)+ and CD45+ cell frequency per region of interest (ROI) group and tissue origin (A). The colour-labelled modules of co-expressed genes were evaluated for over-representation of biological processes, of which 6/8 modules were enriched in known GO pathways (B). HBV, hepatitis B virus.

Credit

Amy Cross, James M Harris, Edward Arbe-Barnes, Colin Nixon, Rageshri Dhairyawan, Andrew Hall, Alberto Quaglia, Fadi Issa, Patrick T F Kennedy, Jane A McKeating, Upkar S Gill, Dimitra Peppa

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CC BY-NC

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