Graphical abstract (IMAGE) Sanford Burnham Prebys Caption This graphical abstract uses images from the study's experiments to highlight major findings regarding the role of a protein called CREB-regulated transcription co-activator (CRTC) in supporting the maintenance of heart structure and function, and how it is likely one of the underlying sources of cardiac hypertrophy. Credit Karen Ocorr Usage Restrictions n/a License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.