Figure8,9 (IMAGE)
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Fig. 8 Phase shift of Per1::luc expressional rhythms in SCN slices following injection of Melapts into both bulbus oculi of Per1::luc Tg mice
Phase shifts following injection of Melapts into bulbus oculi with LED light stimulus at subjective dawn (CT22). SCN slices were obtained from mice injected with Melapts, and bioluminescence was observed for approximately 5 d. The NINJA program was used to calculate phase shifts. The upper direction shows phase advance, whereas the lower direction shows phase delay. Red: phase advance. Blue: phase delay. n = 3, *p < 0.05, Tukey–Kramer test
Fig. 9 Phase shifts measured from Per1::luc expression rhythms in SCN slices from Melapt-injected Per1::lucTg mice
(A) Controls. (B) Injected with Melapt 01. (C) Melapt 02. (D) Melapt 03. (E) Melapt04. (F) Melapt 07. (G) Melapt 09. (H) Melapt 10. (I) Melapt 11. Amplitude was measured at 36−108 h.
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