Biosafety evaluation of peptides in mice. (IMAGE)

Tsinghua University Press

Biosafety evaluation of peptides in mice.

Caption

A. Schematic diagram of biocompatibility analysis of SFK2. B–C. Change in the relative organ weights of liver and kidney in mice after 7 consecutive days of intraperitoneal injection of SFK2. D–I. Changes in liver‐and kidney‐related parameters in mice after 7 consecutive days of intraperitoneal injection of SFK2. Data are expressed as mean ± standard deviation, n = 6. J. Histomorphological observation of the liver and kidney of mice after 7 consecutive days of intraperitoneal injection of different concentrations of SFK2. Scale bar: 100 μm. The same lowercase letter indicates that there is no significant difference (p > 0.05).The different lowercase letter indicates that there is significant difference (p < 0.05). ALT, alanine aminotransferase; ALP, alkaline phosphatase; AST, aspartate aminotransferase; Crea, creatinine; TBIL, total bilirubin.

Credit

Xi Ma, State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University

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