Figure 2 (IMAGE)
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Perturbation of developmentally informed growth models. (a) A schematic illustrates the growth model based on thalamo-salience connectivity rules that change over the developmental age span. Four perturbation models were tested: perturbation applied to the 8-12 years age group, 12-16 years age group, 16-22 years age group, and all age groups, compared to a non-perturbation model. (b) The segregation indices (salience-external and salience-internal) were calculated for each growth model, with percentages indicating the difference compared to the no-perturbation model. (c) Cortical gradients extracted from the simulated affinity matrix of each growth model demonstrate the impact of these perturbations on brain connectivity development.
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Institute for Basic Science
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