(IMAGE)
Caption
Tumors, such as melanoma, release nanovesicles called exosomes (gray) that travel and lodge in the lymph nodes. There they corrupt the behavior of lymph cells. The lymphatic vessels (green) branch out more than usual and allow the tumor cells to survive and migrate to other organs. This process can be seen here in the sentinel lymph node (where metastasis begins to occur) whose structure is shown in red.
Credit
CNIO Microenvironment and Metastasis Group.
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