animation of KIN10 - GRIK1 interaction (VIDEO)
Caption
This animation shows how a flexible loop (orange) on a plant protein known as KIN10 (yellow) allows it to interact with another protein (green) — but only when sugar levels are low. The interaction of the two proteins triggers a cascade of reactions that break down other proteins involved in oil synthesis so the plant can conserve its resources. When sugar levels are high, meaning the plant has abundant resources, a sugar-proxy molecule blocks the loop's swinging motion. That prevents the protein interaction, which keeps the oil-production pathway open.
Credit
Brookhaven National Laboratory
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