Kubo Keratosis Lesions (IMAGE) Kobe University Caption Porokeratosis is a skin disease that leads to the development of red, itchy lesions. In some individuals, these develop all over the body, in some localized in lines, and in some only in one or very few spots. Among around hundred patients who visited the university hospital to get screened by Kubo, the Kobe University researchers found eight patients who didn’t have deficiencies in any of the genes four known to cause the disease, and who also had slightly different symptoms. “All patients kindly cooperated with us to find the cause of the disease,” Kubo says. Credit The American Journal of Human Genetics Usage Restrictions permission required License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.