Bio modelling showing cell entry (VIDEO)
Caption
Video showing how tens of pentameric Shiga toxin B subunits act together to deform the cell boundary to initiate their cell entry. Shiga toxin is secreted by Shigella dysenteriae and is associated with several diseases, such as abdominal pain and watery diarrhea.
Understanding the behaviors of the cell membrane helps in nanotechnological design to prevent toxins and viruses from entering the cell. It also aids in the design of drug delivery vehicles and vaccines that must enter the cell to be effective
Credit
Weria Pezeshkian
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Original content