The single-nucleus RNA sequencing (snRNA-seq) profiling of the cortex, hippocampus, and thalamus of intracranial alternating current stimulation (iACS)-treated rats (IMAGE)

Sichuan International Medical Exchange and Promotion Association

The single-nucleus RNA sequencing (snRNA-seq) profiling of the cortex, hippocampus, and thalamus of intracranial alternating current stimulation (iACS)-treated rats

Caption

(A) Photograph of a rat underling the iACS treatment. (B) Grouping illustration for electrode implantation, iACS and tissue collection. Uniform manifold approximation and projection (UMAP) embedding of analyzed transcriptomes from the rat cortex (C and D), hippocampus (G and H), and thalamus (K and L) tissue annotated by cell type as well as treatment distribution. Distribution and cell numbers of identified cell types, for the cortex (E), hippocampus (I), and thalamus (M). The mRNA expression of NeuN in the iACS-treated cortex (F), hippocampus (J), and thalamus (N) by real-time PCR.

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