b-Cool glycan formation (IMAGE)
Caption
b-Cool formation requires different sugar building blocks, which are depicted as colored hexagons. Specific enzymes link each sugar in a precise manner to form a membrane-anchored glycan (green zigzag). The glycan is likely transported outside the cell to carry out its activity during the early steps of disease progression. The researcher studied the functions of enzymes involved in the formation of b-Cool and analyzed the composition and structure of b-Cool using nuclear magnetic resonance (NMR) and mass spectrometry (MS).
Credit
Yang Su, University of Georgia in Athens; created with BioRender.com
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