OPTN monobodies regulate PINK1/Parkin-mediated mitophagy (IMAGE)

Tokyo Medical and Dental University

OPTN monobodies regulate PINK1/Parkin-mediated mitophagy

Caption

Expression of GFP-Monobodies inhibits OPTN accumulation at the mitophagy contact sites (A) as well as TBK1 activation (B).

Credit

Department of Biomolecular Pathogenesis, TMDU

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.