Animation of IPAN disassembly and subsequent mitosis. (VIDEO)
Caption
A representative cluster of cells with microtubule (MT) protrusions comprises the early interplanar amida network (IPAN). The inset on the left provides an apical view of a subset of the cells shown in a lateral view on the right. Cells with MT protrusions are connected to each other via lateral actin-based filopodia and undergo bundling as some of their MTs disassemble.
The MT subunits generated from disassembly of protrusion MTs are thought to contribute to the formation of the mitotic spindle within the dividing cell
Credit
The animation was created by Erich Brutus.
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License
Original content