schematic (IMAGE) Rice University Caption Siglec-15 is involved in the crosstalk between metastatic bone tumors and immune cells, establishing a vicious cycle that allows immune cell suppression. Credit (Image courtesy of the Xiao lab/Rice University) Usage Restrictions Must credit the Xiao lab/Rice University. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.