Figure 2 (IMAGE) Institute for Basic Science Caption In vivo therapeutic effect and immune restoration by Ce-MSCNVs. (a) Clinical score and paw thickness were significantly reduced in the Ce-MSCNV treatment group. (b) The cartilage structure was well preserved in the Ce-MSCNV treatment group, unlike in the severely damaged control group. (c) Ce-MSCNVs effectively restored the Th17/Treg balance. (d) Tregs induced by Ce-MSCNVs demonstrate CIA-relevant antigen-specific immune suppression. Credit Institute for Basic Science Usage Restrictions Attribution Required License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.