13-Mar-2025 Older adults might be more resistant to bird flu infections than children, Penn research finds University of Pennsylvania School of Medicine Peer-Reviewed Publication Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection against H5N1, and children would benefit more from H5N1 vaccines. Journal Nature Medicine Funder NIH/National Institute of Allergy and Infectious Diseases
13-Mar-2025 Cellular circuit controls how DNA damage is repaired, affecting risk of disease as we age Sanford Burnham Prebys Peer-Reviewed Publication Scientists at Sanford Burnham Prebys and collaborators across the country published findings March 5, 2025, in Nature Communications showing that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like cells to spew inflammatory molecules that can contribute to chronic inflammation in the body. Journal Nature Communications Funder NIH/National Institutes of Health, NIH/National Cancer Institute, California Institute for Regenerative Medicine
13-Mar-2025 Researchers ‘seq’ and find a way to make pig retinal cells to advance eye treatments Morgridge Institute for Research Peer-Reviewed Publication For the first time, researchers developed stem cell-derived pig retinal cells in comparison with human retinal cells, envisioning a path to advance treatments for eye disease and injury. Journal Stem Cell Reports Funder U.S. Department of Defense, NIH/National Eye Institute
13-Mar-2025 Study highlights noninvasive hearing aid Atrium Health Wake Forest Baptist Peer-Reviewed Publication A study from researchers at Wake Forest University School of Medicine highlights a new approach in addressing conductive hearing loss. A team of scientists, led by Mohammad J. Moghimi, Ph.D., assistant professor of biomedical engineering, designed a new type of hearing aid that not only improves hearing but also offers a safe, non-invasive alternative to implantable devices and corrective surgeries. Journal Communications Engineering Funder NIH/National Institute on Deafness and Other Communication Disorders
13-Mar-2025 Re-purposed FDA-approved drug could help treat high-grade glioma Michigan Medicine - University of Michigan Peer-Reviewed Publication A study, published in Cancer Cell, shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug Administration to treat gastrointestinal stromal tumors with a PDGFRA exon 18 mutation as well advanced systemic mastocytosis and indolent systemic mastocytosis. Journal Cancer Cell Funder NIH/National Institutes of Health, NIH/National Cancer Institute, Austrian Science Fund