Substance use disorders are notoriously difficult to treat, as it is challenging to intervene in a drugs’ effect on the brain’s reward pathway without interfering with the pathway’s normal function. In a University of Arizona Health Sciences study, researchers identified a drug that reduced the desire for cocaine in a murine model while keeping the brain’s reward pathways for sugar intact.

New research examines the impact on nonfatal overdoses and addiction treatment in states that received Medicaid waivers to pay for services in so-called institutions of mental diseases.

A collaborative team of researchers led by Dale Zhou, who did his Ph.D. at the University of Pennsylvania's Perelman School of Medicine, and Dani Bassett in Penn's School of Engineering and Applied Science looked at how nearly half a million people around the world use Wikipedia’s knowledge networks. They found stark differences in browsing habits between countries offering insights into cultural differences and potential drivers of curiosity and learning.