Breaking News26 September

If wine is cultivated where forest fires occur more often, such as in Australia or Italy, aromas that make the alcoholic drink unpalatable can develop in the finished product. Until now, it wasn't known why this is so and what happens at the molecular level. A team at Technical University Munich is describing why the smoke aromas are stored in grapes and is thus showing the way for growers to eliminate this degradation in quality.

Helping an adult lose weight leads to significant cost savings at any age, with those savings peaking at age 50, suggests a new Johns Hopkins Bloomberg School of Public Health study.

Scientists at Tokyo Institute of Technology (Tokyo Tech), Nagasaki University have identified four potential protein inhibitors and unlocked drug discovery strategies for the treatment of Chagas disease by using advanced three-dimensional computer simulation by supercomputer TSUBAME in combination with in vitro experiments and X-ray crystallography. Through this "smart drug discovery" in which IT drug discovery and biochemical experiments cooperate, they identified hit compounds for target protein with a hit rate of 20 times or more than conventional High Throughput Screening (HTS) methods.

Compared to other medical settings, emergency patients who are prescribed opioids for the first time in the emergency department are less likely to become long-term users and more likely to be prescribed these powerful painkillers in accordance with The Centers for Disease Control and Prevention (CDC) guidelines. A paper analyzing 5.2 million prescriptions for opioids is being published online today in Annals of Emergency Medicine.

Opioid prescriptions from the emergency department (ED) are written for a shorter duration and smaller dose than those written elsewhere, shows new research led by Mayo Clinic. The study, published today in the Annals of Emergency Medicine, also demonstrates that patients who receive an opioid prescription in the ED are less likely to progress to long-term use.