News Release 

Pseudomonas aeruginosa: A serious threat to human health

Bentham Science Publishers

Book Announcement

No one knows exactly when humans and pathogenic bacteria were encountered with each other. But since then, the war began over life and survival between them. During this time, both sides of the war tried to equip themselves with all their might. Throughout time, sometimes humans and sometimes pathogenic bacteria have been victorious, but the contention has not ended yet. However, some of these pathogenic bacteria are stubborn fighters and require much more attention and unfortunately, humans have been disarmed against some of them. Among them, Pseudomonas aeruginosa is the pathogen that poses a serious threat to human health. The spectrum of its pathogenesis is very wide. So, the infection can range from a simple superficial infection to a deadly infection. Regrettably, it is one of the most resistant bacteria on the planet, which makes it one of the most prominent and ruthless bacterial fighters.

The book 'Toxin-Antitoxin Systems in Pseudomonas aeruginosa' deals with P. aeruginosa and toxin-antitoxin systems in the novel way. This book is recommended not only for interested students but also for those who are interested in research in this field. Currently, P. aeruginosa is one of the most essential topics for researchers due to its high pathogenicity and severe antibiotic resistance. On the other hand, toxin-antitoxin systems are considered as one of the most potentially novel antimicrobial targets. In recent years, several scientists have studied the toxin-antitoxin systems in P. aeruginosa and their role in pathogenicity, which have also achieved valuable results. Therefore, this book attempts to acquaint the readers with the P. aeruginosa as well as one of its most precious therapeutic potentials. However, studies in this area are very rare and limited, but this book tries to provide comprehensive information to the readers.

The chapters of 'Toxin-Antitoxin Systems in Pseudomonas aeruginosa' are designed in such a way that even readers who have no knowledge of the subject of this book can get acquainted with it throughout the book. Accordingly, the contents of the book have been categorized in three main parts.

First, P. aeruginosa has been introduced in different aspects. In this section, readers will become familiar with this microorganism by studying the structure, pathogenicity, antibiotic resistance, and other features of this bacterium. It allows the readers to have almost complete information about the P. aeruginosa. Second, classification, structures and roles of toxin antitoxin systems in pathogenicity are explained, which determines how they are involved in the gene regulation and pathogenicity of the bacteria. Therefore, the reader will understand the importance and necessity of recognizing these systems. Third, well-known toxin-antitoxin systems and their functions have been discussed in P. aeruginosa.

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About the Editors:

Mina Mahmoudi is a researcher at the Department of Medical Microbiology at Ilam University of Medical Sciences (IUMS). She completed a master's degree in medical microbiology at IUMS, and her undergraduate study was in the field of cellular and molecular biology-microbiology at the Islamic Azad University of Hamedan. Her research interests lie in the areas of toxin-antitoxin system, biofilm formation, persister cell, drug tolerance, and target discovery. Currently, due to the increasing ineffectiveness of existing antibiotics, Dr. Mahmoudi is trying to expand her research to identify novel antimicrobial targets. She hopes to give her congeners a healthier and easier life by fighting microbes that threaten human societies.

Sobhan Ghafourian completed his PhD in medical microbiology at the University Putra Malaysia in 2014. Dr. Ghafourian is an associate professor at the Department of Microbiology at the Ilam University of Medical Sciences, Ilam, Iran. His research is mainly focused on toxin-antitoxin systems, antimicrobial resistance, antimicrobial drug discovery, target discovery, and persister cells.

Behzad Badakhsh completed his subspecialty of gastroenterology and hepatology at Iran University of Medical Sciences, Tehran, Iran, in 2018. Dr. Badakhsh is an associate professor at the Department of Gastroenterology at the Ilam University of Medical Sciences, Ilam, Iran. His research interests include antimicrobial target discovery in bacteria, gut microbiota, and H.pylori.

Keywords: Pseudomonas aeruginosa, pathogen, toxin-antitoxin systems, microorganism, pathogenic bacteria, antibiotic resistance, pathogenicity

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