Child vaccination rates declined during COVID-19 pandemic

PASADENA, Calif. -- The numbers of recommended vaccine doses, including measles vaccine, administered to children decreased dramatically after the declaration of a national state of emergency on March 13, 2020, due to the COVID-19 pandemic, according to a Kaiser Permanente study published in Pediatrics. While the decrease was lower and recovered in children under 2 years of age, it was more severe and persistent in older children.

"When vaccination rates decline, we worry about an increase in vaccine-preventable diseases that can be harmful to children," said the study's lead author, Bradley Ackerson, MD, a Kaiser Permanente South Bay Medical Center pediatric infectious disease specialist and an investigator with the Kaiser Permanente Southern California Department of Research & Evaluation's vaccine team. "Also, we know there has been a reduction in childhood vaccinations worldwide, and as COVID-19 restrictions are relaxed, there will be an increased risk of outbreaks due to vaccine-preventable diseases among children returning from outside the United States, unless children here are vaccinated."

To determine the trends in vaccination, researchers assessed the uptake and coverage for recommended vaccines including measles among nearly 1 million children from birth to18 years at Kaiser Permanente in Southern California. Vaccination coverage is a measure of the proportion of children vaccinated at specific ages, while vaccine uptake is the number of children getting vaccinated. The study showed that vaccination coverage continued to decline even after vaccine uptake recovered because vaccinations did not return to pre-pandemic levels in most age groups, causing the number of unvaccinated children continued to grow. Researchers also looked at measles vaccination rates separately because measles is particularly contagious and causes severe disease in all age groups.

The researchers compared January through August 2020 with the same period in 2019. The patient group was 49% female, 24% non-Hispanic white, and nearly 50% Hispanic.

• While overall vaccinations declined in all children during the pandemic period in 2020 compared with 2019, they recovered completely in children under 2 by May. They partially recovered in older children.
• After an initial decline in measles vaccinations of up to 93% among children aged 2 to 18 years during the pandemic, measles vaccinations partially recovered, but remained lower in 2020 than in 2019.
• While measles vaccination coverage was unchanged in the 7-year-old patients, there was a significant decrease in measles vaccination coverage among 16-month-old patients that worsened over time.

"While the severe decrease in measles vaccine uptake among children improved, measles vaccine uptake remained substantially reduced, so the population of unvaccinated children is continuing to grow," Dr. Ackerson said. "The decrease in measles vaccine uptake is very concerning as even a 2% to 5% reduction in measles vaccination coverage is projected to result in exponential increases in measles outbreaks."

At Kaiser Permanente in Southern California, clinicians are addressing childhood vaccination concerns by contacting members whose children are due for vaccination and providing reassurance about safety measures being taken for vaccination visits. Besides implementing masking, distancing, and hygiene measures, sick visits are separated from well visits by location and time. Drive-through vaccinations were also provided at certain facilities

Study co-author Robert Riewerts, MD, a pediatrician with the Southern California Permanente Medical Group, said he understands that parents may feel uneasy about taking their children to medical offices for vaccinations. However, "This is a case where the benefit of vaccination far outweighs the risk of visiting a medical office. Our medical offices are taking every precaution to keep kids and their families safe."

###

Funding for this study was provided internally through the Kaiser Permanente Southern California Department of Research & Evaluation.

In addition to Dr. Ackerson and Dr. Riewerts, other authors on this study are Lina S. Sy, MPH; Sungching Glenn, MS; and Lei Qian, PhD, with the Department of Research & Evaluation; and Claire H. Park, MPH, and Steven J. Jacobsen, MD, PhD, formerly of the Department of Research & Evaluation.

Kaiser Permanente scientists who study vaccination have published findings that have been cited more than 50 times in recent guidelines and consensus statements. Our vaccines research has directly influenced national vaccines policies.

Kaiser Permanente is committed to helping shape the future of health care. We are recognized as one of America's leading health care providers and not-for-profit health plans. Founded in 1945, Kaiser Permanente has a mission to provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. We currently serve 12.4 million members in 8 states and the District of Columbia. Care for members and patients is focused on their total health and guided by their personal Permanente Medical Group physicians, specialists, and team of caregivers. Our expert and caring medical teams are empowered and supported by industry-leading technology advances and tools for health promotion, disease prevention, state-of-the-art care delivery, and world-class chronic disease management. Kaiser Permanente is dedicated to care innovations, clinical research, health education, and the support of community health.