News Release 

Failure to rescue a major driver of excess maternal mortality in Black women

Site of delivery represents a focal point for interventions to reduce racial and ethnic disparities

Columbia University's Mailman School of Public Health

Research News

In a study of over 73 million delivery hospitalizations during a 19-year period in the United States, researchers at Columbia University Mailman School of Public Health and Columbia University Irving Medical Center found that failure to rescue from severe maternal morbidity contributes more than a half of the 3-fold difference in maternal mortality between Black women and White women. Failure to rescue refers to death resulting from severe maternal morbidity such as eclampsia, acute heart failure, and sepsis. The findings are published in the journal Obstetrics and Gynecology.

"Despite the continuing decrease in failure to rescue over the entire study period, racial and ethnic disparities in failure to rescue persisted, underscoring the need to identify factors accounting for these disparities and to identify interventions to avoid potentially preventable deaths in racial and ethnic minority women," said Jean Guglielminotti, MD, PhD, in the Department of Anesthesiology, Columbia Medical Center, and lead author.

Using community hospital discharge records from the National Inpatient Sample of the Healthcare Cost and Utilization Project, the researcher analyzed data of delivery hospitalizations with severe maternal morbidity beginning in 1999-2017, identified using Centers for Disease Control and Prevention diagnosis codes and include 21 serious medical conditions during or immediately after childbirth.

Among the 993,864 women with severe maternal morbidity, 4,328 (0.4 percent) died, accounting for 88 percent of deaths during delivery. The severe maternal morbidity rate in Black women (2.2 percent) was higher than in Hispanic or White women, at 1.5 percent and 1.1 percent, respectively. Women with severe maternal morbidity who died were more likely to be older, and have nonprivate insurance, lower household income, and a higher obstetric comorbidity index. They also were more likely to be transferred from another acute care hospital, be admitted during a weekend, have a cesarean birth, or deliver in a large-bed size hospital or in an urban teaching hospital.

"Our study confirms that excess maternal mortality continues to be a serious public health problem and improving the quality of obstetric care, especially for Black and other minority women, could help substantially decrease maternal mortality and reduce racial and ethnic disparities in maternal mortality in the United States. " said Guohua Li, MD, DrPH, professor of Anesthesiology and Epidemiology at Columbia Mailman School of Public Health, and senior author.

Guglielminotti and Li make the point that hospital culture, team attitudes and behaviors toward patient safety and communication, and favorable nursing environments may be important determinants of maternal health outcomes.


Co-authors are Cynthia Wong of the University of Iowa and Alexander Friedman of Columbia University Vagelos College of Physicians and Surgeons.

Columbia University Mailman School of Public Health

Founded in 1922, the Columbia University Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Columbia Mailman School is the seventh largest recipient of NIH grants among schools of public health. Its nearly 300 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change and health, and public health preparedness. It is a leader in public health education with more than 1,300 graduate students from 55 nations pursuing a variety of master's and doctoral degree programs. The Columbia Mailman School is also home to numerous world-renowned research centers, including ICAP and the Center for Infection and Immunity. For more information, please visit

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.