Public Release: 

Possible connection between cardiovascular disease and living near oil and gas wells

Colorado School of Public Health pilot study finds early indicators of disease are greatest in those living in areas with high O&G activity

University of Colorado Anschutz Medical Campus

AURORA, Colo. (Dec. 11, 2018) - Researchers at the Colorado School of Public Health have found a possible connection between the intensity of oil and gas exploration in an area and early indicators of cardiovascular disease among nearby residents.

In a pilot study of 97 people in Fort Collins, Greeley and Windsor, the scientists found that those who lived in areas of more intense oil and gas development showed early signs of cardiovascular disease (CVD), including higher blood pressure, changes in the stiffness of blood vessels, and markers of inflammation.

The study was published this month in the journal Environmental Research.

"We are not sure whether the responsible factor is noise or emissions from the well pads or something else, but we did observe that with more intense oil and gas activity around a person's home, cardiovascular disease indicator levels increased," said the study's lead author Lisa McKenzie, PhD, MPH, of the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus.

From Oct. 2015 to May 2016, the researchers measured indicators of CVD in 97 men and women from Fort Collins, Greeley and Windsor who did not smoke tobacco or marijuana. The participants did not have jobs that exposed them to dust, fumes, solvents or oil or gas development activities. None had histories of diabetes, chronic obstructive pulmonary disease or chronic inflammatory disease like asthma or arthritis. CVD is the leading cause of mortality in the U.S. with more than 900,000 deaths in 2016.

"While behavioral and genetic factors contribute to the burden of CVD, exposure to environmental stressors, such as air pollution, noise and psychosocial stress also contribute to cardiovascular morbidity and mortality," according to the authors.

One increasingly common source of these stressors is extraction of oil and gas in residential areas. Advances in fracking, horizontal drilling, and micro-seismic imaging have opened up many previously inaccessible areas for exploration. Some of those wells are in heavily populated areas.

"More than 17.4 million people in the U.S. now live within one mile of an active oil and gas well," McKenzie said.

Previous studies have shown that short and long-term exposure to the kind of particulate matter emitted from oil and gas operations may be associated with increases in cardiovascular disease and death.

At the same time, noise levels measured in communities near these facilities have exceeded levels associated with increased risk of CVD and hypertension, the study said.

This study is the first to investigate the relationship between oil and gas development and CVD. But the results are consistent with an increase in the frequency of cardiology inpatient hospital admissions in areas of oil and gas activity in Pennsylvania.

"Our study findings support the use of these indicators of cardiovascular disease in future studies on oil and gas development in residential areas," McKenzie said.

Those indicators included blood pressure, arterial stiffening and early markers of inflammation.

McKenzie acknowledged the limitations of the small sample size, saying that the results demonstrate the need for a much larger study.

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The study co-authors include: John L. Adgate, Department of Environmental and Occupational Health, Colorado School of Public Health; James Crooks, Division of Biostatistics and Bioinformatics, National Jewish Health, Department of Epidemiology, Colorado School of Public Health; Jennifer L. Peel, Department of Environmental and Occupational Health, Colorado School of Public Health, Department of Epidemiology, Colorado School of Public Health, Department of Environmental and Radiological Health Sciences, Colorado State University; Benjamin D. Blair, Department of Environmental and Occupational Health, Colorado School of Public Health; Stephen Brindley, Department of Environmental and Occupational Health, Colorado School of Public Health; William B. Allshouse, Department of Environmental and Occupational Health, Colorado School of Public Health; Stephanie Malin, Department of Sociology & Colorado School of Public Health, Colorado State University.

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