Researchers report that blood samples from 26 out of 32 Sierra Leonean survivors of the 2013-2016 Ebola outbreak, ages 15-53 years, exhibited cytotoxic T cell responses to Ebola-specific proteins, with 25 of the 26 samples responsive to viral nucleoprotein (NP) and 10 of the 26 samples responsive to viral glycoprotein (GP), suggesting that a vaccine including both NP and GP might help elicit cell-mediated immunity against Ebola.
Article #18-06200: "Analysis of CD8+ T cell response during the 2013-2016 Ebola epidemic in West Africa," by Saori Sakabe et al.
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Journal
Proceedings of the National Academy of Sciences