Bottom Line: A study of mammography data for more than 300,000 women suggests cases of breast cancer diagnosed after a negative screening mammogram were more likely to be associated with poor prognosis than those cancers diagnosed after a positive screening mammogram.
Why The Research Is Interesting: The rate of breast cancer after negative mammography results is small but the likelihood these cases can be associated with poor prognosis highlights the need for early detection.
Authors: Anne Marie McCarthy, Ph.D., of Massachusetts General Hospital and Harvard Medical School, Boston, and coauthors
Study Design: This was an observational study. Researchers were not intervening for purposes of the study and they cannot control natural differences that could explain study findings.
To Learn More: The full study is available on the For The Media website.
(doi:10.1001/jamaoncol.2018.00)
Editor's Note: The article contains funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
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JAMA Oncology