Public Release: 

Strategies to combat the opioid epidemic

American Chemical Society

The opioid epidemic is ravaging lives and tearing families apart. Overdose deaths from heroin, fentanyl and misused prescription painkillers have tripled in the past 15 years. Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, explores how abuse-deterring and novel formulations for painkillers in addition to crime-fighting tools to quickly identify opioids could help curb the crisis.

Oxycontin made its debut in 1996 as a prescription pain treatment. By 2004, it had become a leading drug of abuse in the U.S., C&EN reports. To help curb the crisis, drugmakers have begun formulating opioid pills with special coatings or infusions that would make them harder to misuse. But these abuse-deterrent opioids are nearly double the price of the original formulation - literally a high price for patients who need the medications for relief from extreme pain. And whether they effectively reduce opioid misuse remains to be seen. In other pharmaceutical efforts to help combat the epidemic, some labs are looking to replace opioids altogether with novel and equally effective painkillers.

On another front in this fight, scientists are developing powerful opioid detectors to help law enforcement officers quickly identify the drugs on the street and minimize officers' own risk of exposure. Powders can easily spill onto clothing or become airborne, increasing the risk of accidental inhalation or ingestion by law enforcement officers and lab technicians. With new instruments at their disposal, police do not even need to open a bag or come into contact with the drug to identify it.

###

The articles are freely available below.

"Looking beyond opioids for safer pain relief"

"Powerful detection technology for powerful new street drugs"

"Abuse-deterrent opioids: Worth the effort and cost?"

"How chemists are responding to the opioid epidemic"

The American Chemical Society, the world's largest scientific society, is a not-for-profit organization chartered by the U.S. Congress. ACS is a global leader in providing access to chemistry-related information and research through its multiple databases, peer-reviewed journals and scientific conferences. ACS does not conduct research, but publishes and publicizes peer-reviewed scientific studies. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.

Follow us on Twitter | Facebook

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.