News Release

Opioid abuse can be treated successfully in primary care settings, study finds

Peer-Reviewed Publication

RAND Corporation

Combining substance abuse treatment with regular medical care can successfully treat people with opioid or alcohol addiction, providing an option that might expand treatment and lower the cost of caring for people caught up in the nation's opioid epidemic, according to a new RAND Corporation study.

Patients who enrolled in a program that combined substance abuse treatment with primary medical care were more than twice as likely to receive treatment for opioid or alcohol abuse, as compared to peers who received usual primary care services, according to the study.

The patients in the collaborative care model also were significantly more likely to report abstinence from opioids or alcohol six month after beginning care, a key marker to successful recovery. The findings are published online by the journal JAMA Internal Medicine.

"This new model of integrating treatment for substance use disorders with a patient's primary medical care could expand access to drug treatment at a lower cost and in a more accessible fashion," said Dr. Katherine E. Watkins, the study's lead author and a senior physician scientist at RAND, a nonprofit research organization. "This is a way to increase access to evidence-based substance use treatment, without having to convince patients to go to a specialized drug treatment center."

Deaths in the United States are rising from increases in drug overdoses and alcohol-related liver disease, yet many substance use disorders continue to be under identified and undertreated.

While treatment in specialty care settings is important for people who have severe dependence, researchers say that access to such care is limited and the stigma associated with drug treatment means that specialty care alone is insufficient to address the nation's treatment needs.

The RAND study involved 377 people with opioid or alcohol abuse disorders who received medical care at two locations operated by a safety-net medical provider in the Los Angeles area. The clinics were part of a federally qualified health center.

Participants were randomly assigned to receive their medical care from either the clinics' usual primary care providers or from providers who were partnered with therapists and care coordinators who received special training to provide evidence-based substance use treatment.

The collaborative care system was designed to increase delivery of a six-session brief psychotherapy treatment and/or medication-assisted treatment to reduce cravings for opioids or alcohol. Patients receiving usual care were told the clinic provided substance use treatment and were given a phone number to schedule an appointment, as well as a list of community referrals.

Most of the patients in the study had challenges that were viewed as an obstacle to receiving successful treatment, with nearly half of the group being homeless at the time of enrollment.

Among those treated in the collaborative care model, 39 percent received some type of substance abuse treatment, compared to 16.8 percent among those treated in the usual primary care system.

After six months, 32.8 of the participants in the collaborative care model reported that they had abstained from opioids or alcohol in the previous month, compared to 22.3 percent treated in the usual primary care system. Researchers say that among people with substance abuse problems, abstinence is linked to a lower likelihood of relapse compared with nonproblem use.

"Our findings suggest that it is possible to successfully treat people who are addicted to opioids or alcohol in a primary care setting," Watkins said. "The collaborative care model can be a lower-cost and more-accessible way to treat opioid addiction than expanding the nation's supply of specialty care clinics."

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Support for the research was provided by the National Institute on Drug Abuse.

Other authors of the study are Allison J. Ober, Claude Setodji, Karen Chan Osilla, Sarah B. Hunter, Colleen M. McCullough, Kirsten Becker and Praise O. Iyiewuare, all of RAND; Dr. Karen Lamp and Mimi Lind of the Venice Family Clinic, Dr. Allison Diamant of RAND and UCLA; Dr. Keith Heinzerling of UCLA; and Dr. Harold Alan Pincus of RAND, Columbia University and New York-Presbyterian Hospital.

RAND Health is the nation's largest independent health policy research program, with a broad research portfolio that focuses on health care costs, quality and public health preparedness, among other topics.


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