image: Antibodies transmitted from the mother to the chick through the egg can persist in the chick for several weeks after hatching, even several years after the mother's exposure to a vaccine, which has implications for the use of vaccines for conservation in natural populations of such long-lived species. view more
Credit: Raül Ramos
A group of researchers from the University of Barcelona (Spain), the CNRS in Montpellier (France) and Princeton University (USA) report in The American Naturalist that the vaccination of females of a long-lived seabird species, the Cory's shearwater, results in levels of antibodies that allow their transmission to their offspring for several years and could provide several weeks of protection after hatching to these offspring.
Over a period of 6 years, in the Canary Archipelago (Spain), the researchers tracked the immune status of a large number of adults and chicks, a feat rendered possible by the breeding site fidelity of this species. The results show that the temporal persistence of maternally transferred antibodies in nestlings is highly dependent on the level at hatching. Furthermore, a second vaccination efficiently boosts the level of antibodies in females and thus their transfer to offspring.
This long persistence in adults and chicks has potentially strong implications for the use of vaccination as a conservation tool in natural populations of other long-lived species, such as albatrosses, threatened by specific emerging infectious disease agents. More generally, the results also highlight the need to consider the temporal dynamics of immune responses when studying the evolutionary ecology of host-parasite interactions. Because immunity may last and be transmitted for several years, the development of specific immunity early in life can have unforeseen consequences several years later when individuals from the next generation face exposure to the same disease agent.
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Raül Ramos, Romain Garnier, Jacob González-Solís, and Thierry Boulinier, "Long Antibody Persistence and Transgenerational Transfer of Immunity in a Long-Lived Vertebrate." The American Naturalist Vol. 184, No. 6 (December 2014), pp. 764-776. http://www.jstor.org/stable/10.1086/678400
Since its inception in 1867, The American Naturalist has maintained its position as one of the world's premier peer-reviewed publications in ecology, evolution, and behavior research. Its goals are to publish articles that are of broad interest to the readership, pose new and significant problems, introduce novel subjects, develop conceptual unification, and change the way people think. AmNat emphasizes sophisticated methodologies and innovative theoretical syntheses--all in an effort to advance the knowledge of organic evolution and other broad biological principles.