News Release

Optimal parameter of Neiguan acupuncture for cerebral infarction

Peer-Reviewed Publication

Neural Regeneration Research

Acupuncture at Neiguan

image: This image shows acupuncture at Neiguan (PC6) with a lifting and thrusting frequency of 3 Hz and long duration of 60 seconds could significantly reduce cerebral infarction in rat models of middle cerebral artery occlusion. view more 

Credit: <i>Neural Regeneration Research</i>

The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture, but have also affected the specificity of acupoints. As reported in a recent study published in the Neural Regeneration Research (Vol. 8, No. 28, 2013), acupuncture at Neiguan (PC6) was performed using a custom lifting- and thrusting-controlled machine. A frequency of 1, 2, or 3 Hz and duration of 5, 60, or 180 seconds were used to observe cerebral blood flow and ratio of infarct volume recovery. An orthogonal design was used to sift the optimal parameter of Neiguan acupuncture. Experimental results showed that stimulation at Neiguan with a frequency of 1 Hz and long duration of 180 seconds or 2/3 Hz and long duration of 5/60 seconds significantly increased cerebral blood flow and decreased the ratio of infarct volume.

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Article: " Orthogonal design to sift the optimal parameter of Neiguan acupuncture for cerebral infarction," by Yanan Zhang1, Sha Yang2, 3, 4, Xiaonong Fan2, 3, 4, 5, Shu Wang2, 3, 4, Nina He6, Lingxin Li7, Ding Luo8, Xuemin Shi1 (1 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 2 Acupuncture and Moxibustion Research Institute of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 3 Key Laboratory of Cerebropathy Acupuncture Therapy of State Administration of Traditional Chinese Medicine, Tianjin 300193, China; 4 Tianjin Key Laboratory of Acupuncture & Moxibustion Science, Tianjin 300193, China; 5 Three-level Laboratory of Acupuncture Dose-Effect Relationship, State Administration of Traditional Chinese Medicine, Tianjin 300193, China; 6 Wuhai Hospital of Traditional Chinese Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China; 7 Department of Rehabilitation Medicine, West China Medical School, West China Hospital Sichuan University, Chengdu 610041, Sichuan Province, China; 8 Postgraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China)

Zhang YN, Yang S, Fan XN, Wang S, He NN, Li LX, Luo D, Shi XM. Orthogonal design to sift the optimal parameter of Neiguan acupuncture for cerebral infarction. Neural Regen Res. 2013;8(28):2641-2648.

Contact:

Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
http://www.nrronline.org/

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