Hyperhomocysteinemia and abnormal blood lipids are independent risk factors for stroke. However, whether both factors exert a synergistic effect in the onset of stroke remains unclear. As reported in the Neural Regeneration Research (Vol. 8, No. 31, 2013), a study by Dr. Xiaoyong Sai and colleagues from Chinese PLA General Hospital is a retrospective analysis of inpatients across a 5 year period from the Chinese PLA General Hospital, based on a matched pairs case control design. Their results indicate that elevated homocysteine and abnormal blood lipids exert synergistic effects in the onset of stroke. Patients with elevated homocysteine levels and abnormal blood lipids are predisposed to stroke.
Article: " Synergistic effects of elevated homocysteine level and abnormal blood lipids on the onset of stroke," by Lu Hao1, Liming Chen1, Xiaoyong Sai2, 3, Zhefeng Liu1, Guang Yang1, Rongzeng Yan1, Lili Wang1, Caiyun Fu1, Xuan Xu1, Zhenzhen Cheng1, Qiang Wu1, Shuzhang Li1(1 Chinese PLA General Hospital, Beijing 100853, China; 2 Institute of Geriatrics, Chinese PLA General Hospital, Beijing 100853, China; 3 Beijing Key Laboratory of Geriatrics, Beijing 100853, China)
Hao L, Chen LM, Sai XY, Liu ZF, Yang G, Yan RZ, Wang LL, Fu CY, Xu X, Cheng ZZ, Wu Q, Li SZ. Synergistic effects of elevated homocysteine level and abnormal blood lipids on the onset of stroke. Neural Regen Res. 2013;8(31):2923-2931.
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Neural Regeneration Research
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Journal
Neural Regeneration Research