News Release

Abnormal activation of the occipital lobes in major depressive disorder patients

Peer-Reviewed Publication

Neural Regeneration Research

Functional MRI of Brain

image: Functional MRI showed that the activation of some regions in the frontal lobe, temporal lobe, parietal lobe, limbic lobe was enhanced when the patients were watching negative pictures compared with normal controls. view more 

Credit: <i>Neural Regeneration Research</i>

A recent study published in the Neural Regeneration Research (Vol. 8, No. 18, 2013) combined cognition tasks and functional MRI, and designed multiple repeated event-related tasks; additionally, using the International Affective Picture System-based event-related tasks, this study investigated brain functional characteristics of major depressive disorder patients exhibiting, negative bias brain imaging changes and cognitive dysfunction, as well as their relationship based on biased quantitative data. Results show that (1) the number of error responses was calculated to identify bias of emotion recognition between patients with major depressive disorder and normal controls, suggesting that the depressed patients exhibited negative bias towards emotion task stimuli based on quantitative data; (2) the activation of the occipital lobe was attenuated in depressed patients when doing emotion tasks; (3) Deficits in the occipital lobes may be an initiating factor for depression onset, which results in attention deficit disorder and cognitive dysfunction.

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Article: " Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients," by Jianying Li1, Cheng Xu2, Xiaohua Cao1, Qiang Gao2, Yan Wang1, Yanfang Wang1, Juyi Peng1, Kerang Zhang1 (1 Department of Mental Health, First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China; 2 MRI Room, Shanxi Provincial People's Hospital, Taiyuan 030012, Shanxi Province, China)

Li JY, Xu C, Cao XH, Gao Q, Wang Y, Wang YF, Peng JY, Zhang KR. Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients. Neural Regen Res. 2013;8(18):1693-1701.

Contact:

Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
http://www.nrronline.org/

Full text: http://www.sjzsyj.org:8080/Jweb_sjzs/CN/article/downloadArticleFile.do?attachType=PDF&id=638


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