News Release

Education for kidney failure patients may improve chances living donor transplantation

More transplant knowledge and motivation linked with greater success in obtaining a living donor transplant

Peer-Reviewed Publication

American Society of Nephrology

Highlights

  • In an analysis of 695 patients with kidney failure, Blacks had received less transplant education, were less knowledgeable about transplantation, and were less willing to pursue deceased or living donor transplantation than Whites.

  • Patients who began a transplant evaluation process with a greater knowledge of transplantation and greater motivation to receive living donor transplants were ultimately more successful at receiving a living donor transplant.

  • In 2010, a total of 28,662 kidney transplants took place in the U.S. Of those, only 6,809 were from living donors.

Washington, DC (March 21, 2013) —Patients with kidney failure who have greater transplant knowledge and motivation are ultimately more likely to receive a kidney transplant from a living donor, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The findings suggest that improving patient education may help reduce disparities in transplantation.

A kidney transplant is the best treatment for patients with kidney failure, offering patients a longer and healthier life than dialysis. Also, a kidney from a living donor offers patients a longer and healthier life than a kidney from a deceased donor. Add to this the fact that there is an enormous shortage of available kidneys from deceased donors and it becomes clear that patients should be encouraged to find living relatives or other individuals willing to donate kidneys to them.

"When we think about how to help more kidney patients receive transplants, we know that there are characteristics that can be modified—like how much information patients have about transplantation or their transplant knowledge—and characteristics that are more difficult to change or that cannot be changed at all, such as their race and socio-economic status," said Amy Waterman, PhD (Washington University School of Medicine).

To see which modifiable characteristics might be changed to increase transplantations from living kidney donors, Dr. Waterman and her colleagues studied 695 White and Black kidney failure patients who underwent a transplant evaluation process at the Barnes-Jewish Hospital Transplant Center. At the beginning of the process, patients were asked how knowledgeable they were about transplantation and how willing they were to receive a living donor transplant. Patients were followed for six years.

The researchers found that, compared with Whites, Black patients were less prepared when they started the evaluation process. Blacks were less likely to have received transplant education, were less knowledgeable about transplantation, and were less willing to pursue deceased or living donor transplantation. Six years later, the patients who ultimately received living donor transplants were those who started the process with greater transplant knowledge and greater motivation to receive living donor transplants.

"These findings suggest that we can do something to help. Preparing patients well for transplantation, especially patients of color, is a promising way to help more patients successfully get living donor transplants," said Dr. Waterman. "Educational interventions for kidney patients focused on helping improve patients' transplant knowledge and motivation to pursue transplant may reduce or overcome racial disparities in transplantation," she added.

###

Study co-authors include John Peipert, Shelley Hyland, Melanie McCabe, PhD, Emily Schenk, and Jingxia Liu, PhD.

Disclosures: The authors reported no financial disclosures.

The article, entitled "Modifiable Patient Characteristics and Racial Disparities in Evaluation Completion and Living Donor Transplant," will appear online at http://cjasn.asnjournals.org/ on March 21, 2013, doi: 10.2215/CJN.08880812.

The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.

Founded in 1966, and with more than 13,500 members, the American Society of Nephrology (ASN) leads the fight against kidney disease by educating health professionals, sharing new knowledge, advancing research, and advocating the highest quality care for patients.


Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.