News Release

Noninvasive brain stimulation helps curb impulsivity

NeuroImage study demonstrates significant improvement in patients' inhibitory control

Peer-Reviewed Publication

Elsevier

London, 15 June 2011 - Inhibitory control can be boosted with a mild form of brain stimulation, according to a study published in the June 2011 issue of Neuroimage, Elsevier's Journal of Brain Function. The study's findings indicate that non-invasive intervention can greatly improve patients' inhibitory control. Conducted by a research team led by Dr Chi-Hung Juan of the Institute of Cognitive Neuroscience, National Central University in Taiwan, the research was sponsored by the National Science Council in Taiwan, the UK Medical Research Council, the Royal Society Wolfson Merit Award, and a Fulbright Award.

The study demonstrates that when a weak electrical current is applied over the front of participants' scalps for ten minutes, it greatly improved their ability to process responses – effectively jumpstarting the brain's ability to control impulsivity. The treatment has the potential to serve as a non invasive treatment for patients with conditions such as attention-deficit hyperactivity disorder (ADHD), Tourette's syndrome, drug addictions, or violent impulsivity.

Professor Chi-Hung Juan who led the research team noted, "The findings that electrical stimulation to the brain can improve control of their behavioral urges not only provide further understanding of the neural basis of inhibitory control but also suggest a possible therapeutic intervention method for clinical populations, such as those with drug additions or ADHD, in the future".

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Notes to editors

Modulating inhibitory control with direct current stimulation of the superior medial frontal cortex. NeuroImage (2011). Tzu-Yu Hsu, Lin-Yuan Tseng, Jia-Xin Yu, Wen-Jui Kuo, Daisy L... Hung, Ovid J.L. Tzeng, Vincent Walsh, Neil G. Muggleton and Chi-Hung Juan. doi:10.1016/j.neuroimage.2011.03.059

About Neuroimage

NeuroImage, a Journal of Brain Function, provides a vehicle for communicating important advances, using imaging and modelling techniques to study structure-function relationships in the brain. The focus of NeuroImage is on brain systems; however, we are happy to consider papers dealing with structure and function at the microscopic level; if they inform the systems level. The main criterion, on which papers are judged, is to what extent does the scientific contribution advance our understanding of the mechanisms of brain function and how this function depends upon its structure and architecture. These mechanisms may operate in health and disease; therefore, NeuroImage welcomes clinical neuroscience papers that are framed to address mechanisms explicitly. The journal publishes original research articles, papers on methods or modelling, theory and position papers that describe the use of imaging approaches to studying the brain.

About Elsevier

Elsevier is a world-leading publisher of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include SciVerse ScienceDirect, SciVerse Scopus, Reaxys, MD Consult and Nursing Consult, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.

A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).


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