Mapping of neglected tropical diseases critical to control and elimination efforts

To take full advantage of recent increased financial commitments from some governments, international agencies, and philanthropies, accurate and up-to-date mapping of neglected tropical diseases (NTDs) needs to be implemented to help improve the precision of decision-making in NTD control and elimination, says a new editorial, "The Global Atlas of Helminth Infection: Mapping the Way Forward in Neglected Tropical Disease Control," published July 27 in the open-access journal PLoS Neglected Tropical Diseases.

"Better diagnostic tools and new methods of surveillance provide more affordable and realistic opportunities to improve the planning, monitoring, and evaluation of NTD control," write authors Dr. Peter Hotez, President of the Sabin Vaccine Institute and Distinguished Research Professor of The George Washington University Medical Center, Dr. Simon Brooker, Reader in Tropical Epidemiology and Disease Control at the London School of Hygiene and Tropical Medicine and Research Fellow at KEMRI-Wellcome Trust Research Programme in Nairobi, Kenya and Professor Donald Bundy, Coordinator of the Africa Program for Onchocerciasis Control (APOC) and Program Leader in Maternal and Child Health, Population and Nutrition, Africa Region, The World Bank.

The authors assert that, in the past, NTD control has been incomplete and unreliable because of weak disease surveillance systems, and that a "new generation of diagnostics provides a sound foundation for developing reliable, up-to-date maps of the distribution of different NTDs to guide and target resources efficiently. Without such maps, the journey of NTD control will be difficult."

New mapping technologies utilize electronic data entry at the point of collection and rapid transmission of information to a central database using mobile phone technology. Once the data have been compiled, geographical information systems (GIS) simultaneously manage and display the data and include estimates of such variables as temperature, vegetation, and humidity, which affect NTD distribution.

Although many surveys of NTDs have been conducted, the most detailed maps are for onchocerciasis, lymphatic filariasis, and schistosomiasis. These maps are an important resource, but much of their data are old and not easily accessible to policy-makers and managers of public health programs.

The authors highlight a project, the Global Atlas of Helminth Infection (GAHI), which will provide open-access information on the distribution of soil-transmitted helminthiases and schistosomiasis. The GAHI will also highlight the geographical areas where further survey information is required via the GAHI website (http://www.thiswormyworld.org.)

The authors conclude that the development of an integrated Global NTD Atlas for all NTDs would increase the reliability of estimates of disease burden, measure the impact of NTD control efforts, and provide an important planning tool for national control programs.

FINANCIAL DISCLOSURE: SB is funded by a research career development from the Wellcome Trust (no. 081673). SB and PJH also receive funding from the Albert B. Sabin Vaccine Institute's Human Hookworm Vaccine Initiative (HHVI) which is funded by the Bill and Melinda Gates Foundation. This work forms part of the output of the Global Atlas of Helminth Infection which is principally funded by the Partnership for Child Development at Imperial College UK, Deworm the World, and the Wellcome Trust. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

COMPETING INTERESTS: SB is Deputy Editor and PJH is Editor-in-Chief of PLoS Neglected Tropical Diseases. PJH is an inventor on international patents for hookworm and schistosomiasis vaccines. DAPB is Coordinator of the APOC program for the World Bank.

PLEASE ADD THIS LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.plos.org/10.1371/journal.pntd.0000779 (link will go live upon embargo lift)

CITATION: Brooker S, Hotez PJ, Bundy DAP (2010) The Global Atlas of Helminth Infection: Mapping the Way Forward in Neglected Tropical Disease Control. PLoS Negl Trop Dis 4(7): e779. doi:10.1371/journal.pntd.0000779

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