Gastrointestinal (GI) chronic perforations require closure and control of extraluminal collections and sepsis. Covered self-expandable metal stents or plastic stents are an effective method in more than 80% of cases, but have many drawbacks.
Using the newly designed over-the-scope-clip (OTSC) initially intended for hemostasis of gastrointestinal bleeding to close two chronic inveterate external gastric fistulas, a research team from Italy reported the first successful closure of two gastro-cutaneous fistulas. Their study will be published on April 7, 2010 in the World Journal of Gastroenterology.
They concluded that the OTSC may be the least invasive method to close chronic small fistulas or leaks, if prospe¬ctive large comparative studies with fully-covered stents will confirm their observation.
Reference: Iacopini F, Di Lorenzo N, Altorio F, Schurr MO, Scozzarro A. Over-the-scope clip closure of two chronic fistulas after gastric band penetration. World J Gastroenterol 2010; 16(13): 1665-1669 http://www.wjgnet.com/1007-9327/full/v16/i13/1665.htm
Correspondence to: Agostino Scozzarro, MD, Gastroenterology and Endoscopy Unit, Ospedale San Giuseppe, Via dell'Olivella, Albano Laziale, Rome 00041, Italy. a.scozzarro@virgilio.it Telephone: +39-6-93273938 Fax: +39-6-93273216
About World Journal of Gastroenterology
World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection and provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and Hepatology, CAB Abstracts and Global Health. ISI JCR 2008 IF: 2.081. WJG is a weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th day of every month. WJG is supported by The National Natural Science Foundation of China, No. 30224801 and No. 30424812, and was founded with the name of China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998.
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World Journal of Gastroenterology