image: Spectrophotometric readouts of 0.5mM paclitaxel in Neowater and in DMSO. view more
Credit: Revital Mane
18-10-2007, OR YEHUDA, ISRAEL: Do-Coop Technologies Ltd, a privately held corporation involved in the development of water nanotechnology, is pleased to attend the upcoming Second Annual Conference on the Physics, Chemistry and Biology of Water to be held on the 18-21 of October, 2007 in Vermont, USA. Do-Coop invites participants to engage in an open discussion of new approaches to the study of the physical properties of water.
Water nurtures life in all its forms, but not all water in our life systems is equal. Water in a lake, in the sea or in a cup of tea is different from the water in our bodies. This much we do know. Yet science does not yet have a complete understanding as to why intracellular water is different to other water forms. The science of water is subject to conflicting theories. The very structure of water, as an open system and out of equilibrium, makes it an extremely controversial field.
The tools that have been used in the study of other materials no longer comply with the study of water if we wish to make real progress in the research. Do-Coop Technologies Ltd wishes to engage with colleagues and interested parties in a discussion of new, progressive research methods that meet the current needs in the field.
Do-Coop’s own research has led to the development of water-based nanotechnology termed Neowater®. Neowater® is water that displays a clear shift in its physical properties due to the unique organization and interaction between the water, surface and Carbon Dioxide. This stable proprietary structure allows solubility of hydrophobic drugs, stability of proteins and cell cultures, enhancement of biological in vitro and in vivo applications and reduced need for stabilizers and detergents, by solid surface and Carbon Dioxide repackaging in the liquid phase of water in standard conditions (STP). Neowater® uses the surface effect produced by the minute amount of 1015 particles per liter and elevated amount of insoluble Carbon Dioxide to compete on the free bulk water, reducing the entropy of the bulk and producing a colloidal structure within the water, as proven by ITC measurements, ultrasound propagations and Zeta potential.
This new and original approach has far-reaching implications for both the study of the science of water, and in its practical applications. Neowater® gives the industry and the scientific community a stable and unique water-based environment that is more similar to the water that supports life. This enables an improved balance between toxicity and efficacy, ensuring cost-effective and efficient drug development, as well as extended shelf life, IP extension and superior drug delivery.
Nature uses the unique properties of water, earth and air in forming life-supporting niche environments. The chemicals extracted from nature for use in pharmaceuticals are packaged perfectly in the environment. What if technology could replicate these circumstances, creating an environment as close to the natural ideal as possible?
The Do-Coop Technologies team looks forward to the opportunity of an open dialogue of the future directions in the study of the biochemical composition of water with co-participants at the upcoming Scientific Water Meeting in Vermont.