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Gladstone Institutes receives funding for training grant from stem cell institute

Gladstone Institutes

The California Institute for Regenerative Medicine (CIRM) today announced that the J. David Gladstone Institutes and 15 other California nonprofit institutions have received the first year of funding for a three-year program designed to train the next generation of stem cell scientists. These are the first grants awarded by the California stem cell agency.

The Independent Citizens' Oversight Committee (ICOC) approved the training grant applications on September 9, 2005, but they could not be awarded due to litigation impeding the State's ability to sell approved general obligation bonds.

Funding for the grants was drawn from the sale of $14 million of bond anticipation notes (BANs) to six California philanthropic entities. The California Stem Cell Research and Cures Finance Committee approved the BANs this past week.

The J. David Gladstone Institutes will use the funds--the first third of $2.4 million grant-- to develop and implement a CIRM Scholars Training Program, a three-year, stem cell-specific curriculum for 10 postdoctoral fellows.

"We're honored and excited to be part of this historic first round of CIRM grants," said Gladstone Institutes President Robert W. Mahley, MD, PhD. "Our commitment to this promising area of research and to training the next generation of researchers will only be strengthened by our involvement in this program."

Mahley will serve as the director of the program, and Gladstone Institutes Associate Investigator Bruce Conklin, MD, will serve as associate director. Initial trainees will be Gladstone postdoctoral fellows Edward Hsiao, Kathryn Ivey, Jin-A Lee, Gang Li, Laura Saunders, Whittemore Tingley and Yong Zhao. Another three participants will be named in subsequent years, for a total of 10 trainees.

ICOC funds are designed to establish the CIRM Training Program in Stem Cell Research, a three-year program to train pre-doctoral, post-doctoral and clinical fellows at 16 institutions across the state. CIRM awarded three levels of awards--comprehensive, intermediate and specialized--accommodating 169 trainees in programs at small and large institutions throughout California. The Gladstone Institutes applied for and received funding for an intermediate award.

Designed to take advantage of the different strengths of California research institutions, the CIRM program has the goal of educating scholars from a variety of scientific backgrounds, ranging from computation and molecular biology to nanotechnology and clinical medicine. All programs are required to offer at least one course in stem cell biology and disease as well as a course in the social, legal and ethical implications of stem cell research.

In cooperation with a wide spectrum of universities and colleges throughout Northern California, Gladstone will develop a core curriculum of required and elective courses spanning a variety of stem cell research disciplines. Participating institutions include the University of California campuses in San Francisco, Berkeley, Davis, and Santa Cruz, as well as San Francisco State University and the Children's Hospital Oakland Research Institute.

All required and elective courses will be closely coordinated with UCSF programs to facilitate synergies and minimize duplication. The scholars will take a newly designed core course on the ethics of research, as well as a long-established "Ethics and Responsible Conduct of Science" course at UCSF.


CIRM was established in 2004 with the passage of Proposition 71, the California Stem Cell Research and Cures Initiative. The statewide ballot measure, which provided $3 billion in funding for stem cell research at California universities and research institutions, was approved by California voters and called for the establishment of an entity to make grants and provide loans for stem cell research, research facilities, and related research opportunities.

The J. David Gladstone Institutes, affiliated with the University of California, San Francisco (UCSF), is dedicated to the health and welfare of humankind through research into the causes and prevention of some of the world's most devastating diseases. UCSF is a leading university that consistently defines health care worldwide by conducting advanced biomedical research, educating graduate students in the life sciences, and providing complex patient care. Information about the Gladstone Institutes is available at

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